
 Last year was really a bad year for us. My elder sister was diagnosed with 
mitral valve 
stenosis. The doctor said it is severe and she needs a 
mitral valve replacements. To do that she needs to have an open heart surgery. My sister decided she doesn't want to have open heart surgery because she's scared she might not make it. We respect her decision and just do what we can to have her treated through medications. At least it gives her comfort in breathing.
Mitral stenosis is a heart valve disorder that involves a narrowing (
stenotic) or blockage of the opening of the 
mitral valve, which separates the upper and lower chambers on the left side of the heart. 
Mitral stenosis prevents the valve from opening properly. This prevents proper blood flow from moving between the left atrium (upper chamber of the heart) and ventricle (lower chamber of the heart). As the valve area becomes smaller, less blood flows forward to the body. The upper heart chamber swells as pressure builds up and blood may flow back into the lungs, resulting in pulmonary edema (fluid in the lung tissue). You will feel tired and experience shortness of breath, among other problems.
The main cause of 
mitral valve 
stenosis is a childhood infection called rheumatic fever, which is related to untreated strep infections. Rheumatic fever — once common in the United States and still prevalent in developing countries — often scars the 
mitral valve. 
Mitral valve 
stenosis is treatable in people of all ages. Treatment depends on the severity and progression of your condition and your signs and symptoms. If the condition is severe enough, you may need heart surgery to repair or replace the valve. Left unchecked, 
mitral valve 
stenosis can lead to serious heart complications.
You can have 
mitral valve 
stenosis and feel well, or you may have only minimal signs and symptoms for decades. However, mild problems can suddenly get worse. Symptoms may include:
1) Fatigue, especially during times of increased activity. 2) Shortness of breath, especially with exertion or when you lie down. 3) Swollen feet or ankles. 4) Heart palpitations — sensations of a rapid, fluttering heartbeat. 5) Frequent respiratory infections, such as bronchitis. 6) Severe coughing, sometimes coughing up blood. 7) Rarely, chest discomfort or chest pain.
Signs and symptoms of 
mitral valve 
stenosis — which may resemble those of other heart conditions — may appear or worsen anytime you increase your heart rate, such as during exercise. An episode of rapid heartbeats also may accompany these signs and symptoms. Symptoms can also be triggered by pregnancy or other stress on your body, such as a respiratory infection or heart infection (
endocarditis). In 
mitral valve 
stenosis, pressure builds up in the left atrium of the heart and is transmitted back to the lungs resulting in fluid buildup (lung congestion) and shortness of breath. Signs and symptoms of 
mitral valve 
stenosis often appear between the ages of 20 and 50, but they can occur at any age — even during infancy. 
Mitral valve 
stenosis may also produce a number of signs that only your doctor will be able to find. These may include:
1) Heart murmur 2)Lung congestion 3) Irregular heart rhythms (
arrhythmias) 4) Pulmonary hypertension 5) Blood clots.
Our heart consists of four chambers. The two upper chambers, the atria, receive blood. The two lower chambers, the ventricles, pump blood. Blood flows through your heart's chambers, aided by four heart valves: 
Tricuspid valve, Pulmonary valve, 
Mitral valve, and Aortic valve. These valves open and close to let blood flow in only one direction through your heart. The 
mitral valve — which lies between the two chambers on the left side of your heart — consists of two triangular-shaped flaps of tissue called leaflets. The leaflets of the 
mitral valve connect to the heart muscle through a ring of tissue called the annulus. Anchoring the 
mitral valve to the left ventricle are tendon-like cords, resembling the strings of a parachute, called 
chordae tendineae cordis. Heart valves open like a trapdoor. The 
mitral valve is forced open when blood flows from the left atrium into the left ventricle. When all of the blood has gone through the valve, the leaflets swing closed to prevent the blood that has just passed into the left ventricle from flowing backward, in the wrong direction. A defective heart valve can fail to either open or close fully. When a valve doesn't close tightly, blood can flow backward. This backward flow through a valve is called regurgitation (insufficiency). When a valve becomes narrowed and blood flow through it is limited, the condition is called 
stenosis.
Causes of 
mitral valve 
stenosis include:
Rheumatic fever. A complication of strep throat infection, rheumatic fever can damage the 
mitral valve, leading to 
mitral valve 
stenosis later in life. Rheumatic fever is the most common cause of 
mitral valve 
stenosis. It can damage the 
mitral valve in two main ways. The infection may cause the leaflets of the valve to thicken, limiting the valve's ability to open. Or the infection may cause the leaflets of the 
mitral valve to fuse somewhat together, preventing the valve from opening and closing properly. People with rheumatic fever may develop both 
mitral valve 
stenosis and regurgitation. Rheumatic fever is now rare in the developed world thanks to improved antibiotics and other medical care. Congenital heart defect. Some babies are born with a narrowed 
mitral valve and develop 
mitral valve 
stenosis early in life. Babies born with this problem usually require heart surgery to correct the valve. Others are born with a malformed 
mitral valve that puts them at risk of developing 
mitral valve 
stenosis when they're older. In most cases, doctors don't know why a heart valve fails to develop properly in a newborn, infant or child, and it's not something that can be prevented. Congenital 
mitral valve 
stenosis is rare - and even rarer as a single defect. It usually occurs as a component of other heart defects present at birth. Medications. Medications to treat migraine headaches, such as 
ergotamines, can cause 
mitral stenosis. 
Pergolide, a medication used for Parkinson's disease and restless legs syndrome also has been associated with valve problems, including 
mitral stenosis, and has been removed from the market due to risk of heart valve disease. If you have a heart murmur or a diagnosis of 
mitral stenosis, you should discuss use of any medications or supplements with your doctor. Other causes. Rarely, growths, blood clots or tumors can block the 
mitral valve, mimicking 
mitral valve 
stenosis. As you age, excessive calcium deposits can build up around the 
mitral valve, which sometimes causes significant 
mitral valve 
stenosis. Radiation treatment to the chest and some medications also may cause 
mitral valve 
stenosis.
Now, I'm praying that God will extend her life a little bit longer for her to see her two small daughters grow old enough to take care of themselves. For you my dear sister, We'll do the best that we can to help you with your medications. Just keep your eyes on God, Trust Him and always have faith in Him. I know He will take care of you. He already delivers you from your 
appendicitis. God is good all the time. Amen.